Company Overview

Amylyx is a Cambridge-based pharmaceutical company dedicated to the development of therapeutics for the treatment of neurodegenerative disorders. Guided by our core values, we incorporate unconventional approaches through strong partnerships with industry leaders, scientists, doctors and organizations. We work collaboratively across everything we do to positively impact the lives of patients and their families.

Where we began
It all started as a curious dorm room inquiry at Brown University in 2013. After learning that neurodegenerative disease is the result of neuronal death, Amylyx co-founder Josh Cohen couldn’t help but ask himself one simple question: “Why do neurons die?” It seemed like such an obvious starting point yet the solution was nowhere to be found.

After poring over an extensive supply of research, Josh and a classmate, co-founder Justin Klee, posed that question — and started the journey of uncovering the answers. Overcoming obstacle after obstacle, contracting with lab after lab, and formulating test after test, they eventually accumulated sufficient data to pursue the next steps.

In the years since, their partnership has transformed into Amylyx, a rapidly growing pharmaceutical company with the same curiosity and resilience as the day our company began. That simple question considered back in 2013 has led to a clinical reality — a new investigational product, AMX0035, currently in clinical development for the treatment of both amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease.

Our Mission

It is our mission to one day end the suffering caused by neurodegenerative diseases. Every day we strive for better therapies. We question the unquestioned, always in search of new solutions.

Our Values

  • Be audacious
    People living with neurodegenerative diseases are our true north; we envision new possibilities, boldly seek untried approaches, and fearlessly innovate for them.
  • Be curious
    By asking the right questions, listening, and learning, we thrive in a culture of continuous improvement, driven by generously sharing knowledge, making each of us, and the company, better.
  • Be engaged
    We can only understand someone’s needs when we understand their journey. By deeply engaging with the neurodegenerative disease community and their care providers, we know what’s needed.
  • Be accountable
    People living with neurodegenerative diseases always come first. There is no time to wait, and we have a responsibility to turn our most promising ideas into urgent action on their behalf.
  • Be authentic
    When we genuinely care about the work we do and the people with whom we work, we make Amylyx a place where possibility could one day turn into reality.
  • Be the change
    We’ve made some great strides in a short amount of time, but the work has just begun. If you’d like to join us in our mission, you can learn more about our culture and open positions below.



We’re building a culture company
Progress is rarely the result of convention – which is why we’ve been doing things differently since day one. That relentless curiosity has become the foundation for one of the most unique company cultures in life sciences. We are not procrastinators or nay-sayers. We are a group of get-it-done problem solvers dedicated to improving the quality of life for people with neurodegenerative diseases.

Making a difference
Our mission would not be possible without each individual perspective within our team. It’s a culture that uses unconventional thinking for unsolved problems. We learn from one another through our collective experience, and we share a connection in our common purpose.

We are looking for mission-driven builders, thought-provokers, disruptors, audacious minds, and compassionate souls. Most of all, we’re looking for the ones who can roll up their sleeves today in the hopes of making a difference tomorrow. This is just the beginning.

Company Summary
Amylyx Pharmaceuticals
Number of Employees
(617) 682-0917
43 Thorndike Street
Cambridge, MA